Table 1.
Genes required for CoQ biosynthesis
| S. cerevisiaea | C. elegansb | D. melanogasterc | Humansd |
|---|---|---|---|
| COQ1 (YBR003W) | coq-1 (C24A11.9) | qless (cg31005) | COQ1/PDSS1 (COQ1, subunit 1) |
| cg10585 (pdss2) | PDSS2/DLP1 (COQ1, subunit 2) | ||
| COQ2 (YNR041C) | coq-2 (F57B9.4) | coq2 (cg9613) | COQ2 |
| COQ3 (YOL096C) | coq-3 (Y57G11C.11) | coq3 (cg9249) | COQ3 |
| COQ4 (YDR204W) | coq-4 (T03F1.2) | coq4 (cg32172) | COQ4 |
| COQ5 (YML110C) | coq-5 (ZK652.9) | coq5 (cg2453) | COQ5 |
| COQ6 (YGR255C) | coq-6 (K07B1.2) | coq6 (cg7277) | COQ6 (two isoforms: A and B) |
| COQ7/CAT5 (YOR125C) | clk-1 (ZC395.2) | coq7 (cg14437) | COQ7 |
| COQ8 (YGL119W) | coq-8 (C35D10.4) | coq8 (cg32649) | COQ8/ADCK3/CABC1 |
| COQ9 (YLR201C) | coq9 (cg30493) | COQ9 | |
| COQ10 (YOL008W) | coq-10 (R144.13) | coq10 (cg9410) | COQ10A (homolog A) COQ10B (homolog B) |