Table 4. Multivariable-adjusted Odds Ratios (OR) of Breast Cancer within strata defined by Age and Menopausal Status, Collaborative Breast Cancer Study, 1988-2008.
| Characteristic | Cases | Controls | Family history of breast cancer (any versus none) | Body mass index (continuous per 1 kg/m2) | Alcohol intake (continuous per 1 drink per day) | |||
|---|---|---|---|---|---|---|---|---|
|
|
|
|
||||||
| OR a | 95% CI a | OR a | 95% CI a | OR a | 95% CI a | |||
| Premenopausal | ||||||||
| Age <40 | 1,264 | 1,969 | 2.25 | 1.75-2.89 | 0.97 | 0.96-0.99 | 1.11 | 1.01-1.22 |
| Age 40-44 | 1,519 | 1,904 | 1.86 | 1.52-2.29 | 0.98 | 0.97-1.00 | 0.99 | 0.95-1.04 |
| Age 45-49 | 1,766 | 2,061 | 1.74 | 1.45-2.10 | 0.98 | 0.97-1.00 | 1.04 | 0.95-1.14 |
| Age ≥50 | 1,586 | 1,763 | 1.67 | 1.39-2.02 | 0.99 | 0.98-1.00 | 1.17 | 1.05-1.30 |
| Postmenopausal | ||||||||
| Age <55 | 2,000 | 2,571 | 1.68 | 1.43-1.99 | 1.00 | 0.99-1.01 | 1.11 | 1.04-1.20 |
| Age 55-59 | 3,163 | 3,904 | 1.43 | 1.26-1.62 | 1.02 | 1.01-1.03 | 1.14 | 1.07-1.22 |
| Age 60-64 | 3,956 | 4,651 | 1.61 | 1.43-1.80 | 1.02 | 1.01-1.03 | 1.11 | 1.04-1.17 |
| Age 65-69 | 4,200 | 5,024 | 1.64 | 1.47-1.82 | 1.03 | 1.02-1.04 | 1.13 | 1.07-1.20 |
| Age ≥70 | 3,198 | 2,938 | 1.78 | 1.55-2.03 | 1.04 | 1.03-1.05 | 1.25 | 1.15-1.36 |
Abbreviations: CI, confidence interval; OR, odds ratio.
a
Odds ratios are adjusted for age, state of residence, study period, family history of breast cancer, body mass index, alcohol intake, age at menarche, parity, age at first pregnancy, oral contraceptive use, and smoking status.