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. Author manuscript; available in PMC: 2014 Jul 28.
Published in final edited form as: Curr HIV Res. 2013 Sep;11(6):464–472. doi: 10.2174/1570162x113116660053

Fig. (1).

Fig. (1)

The HIV-1 Env trimer structure and the binding sites of broadly neutralizing antibodies (bNAbs) [13, 34, 140]. The picture is adapted from EMD-5418 at a resolution about 11Å in the Electron Microscopy Data Bank. The domain structures are shown in different colors. TM, transmembrane domain; ECD, Ectodomain of gp41; IN, inner domain of gp120; OD, outer domain of gp120, V1, V1 loop and etc.; TAD, trimer association domain. MPER, membrane-proximal external region; CD4-bs, CD4 binding sites; Glycan, glycosylation sites.