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. 2014 Jul 19;13:278. doi: 10.1186/1475-2875-13-278

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Copyright © 2014 Mendonça et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Genotype combinations and outcomes of malaria infection. (A) Univariate linear regression analysis of the different combination of TNF-308G > A, IL6-176G > C, DDX39B-348C > T, and DDX39B-22C > G genotypes. The odds ratios and respective 95% confidence intervals (95% CI) are shown according to each combination of genotypes compared with the other combinations. (B-C) Each symbol represents a single patient, and the lines represent medians and interquartile range. TNF and IL-6 levels in participants with the GC/CC/GG/GG combination compared with the other combinations. The data were compared using the Mann–Whitney test. P values are shown in each panel.