Table 1.
Characteristics of the second series of participants with complicated vivax malaria: Amazonas, Brazil
| |
|
|
Clinical presentation at admission |
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|
| Patient no. | Gender | Age (years) | Major manifestation | Secondary manifestation | Previous treatment | Parasitaemia | Disease duration (days) | Haemoblogin (g/dL) | Total bilirubin (μmol/L) |
| 1 |
M |
59 |
hyperbilirubinaemia |
|
No |
6,222 |
7 |
16.9 |
403.56 |
| 2 |
F |
38 |
hyperlactemia |
|
Yes |
0 |
10 |
10.9 |
30.78 |
| 3 |
M |
31 |
hyperbilirubinaemia |
|
No |
3,298 |
10 |
11.0 |
54.72 |
| 4 |
F |
37 |
hyperbilirubinaemia |
|
No |
67,467 |
7 |
8.9 |
51.30 |
| 5 |
M |
18 |
hyperbilirubinaemia |
|
No |
1,848 |
4 |
13.5 |
165.87 |
| 6 |
M |
45 |
severe anaemia |
hyperbilirubinaemia |
No |
243 |
10 |
6.5 |
138.51 |
| 7 |
F |
40 |
severe anaemia |
|
No |
33,553 |
10 |
7.0 |
27.36 |
| 8 |
M |
66 |
convulsion |
|
Yes |
185 |
14 |
13.0 |
* |
| 9 |
M |
17 |
hyperbilirubinaemia |
|
No |
226 |
6 |
11.9 |
53.01 |
| 10 |
M |
31 |
hyperbilirubinaemia |
|
No |
5,937 |
15 |
13.5 |
165.87 |
| 11 |
M |
1 |
severe anaemia |
|
No |
38,712 |
9 |
5.0 |
8.55 |
| 12 |
M |
26 |
hyperbilirubinaemia |
|
No |
128 |
2 |
10.6 |
61.56 |
| 13 |
F |
4 months |
convulsion |
prostration |
No |
108,033 |
7 |
11.7 |
* |
| 14 |
M |
19 |
severe anaemia |
|
No |
0 |
17 |
6.5 |
15.39 |
| 15 |
M |
50 |
respiratory failure |
|
No |
310 |
5 |
10.1 |
8.55 |
| 16 |
F |
35 |
severe anaemia |
hyperbilirubinaemia |
No |
34,673 |
1 |
4.8 |
138.51 |
| 17 |
F |
41 |
respiratory failure |
|
No |
24,815 |
8 |
9.9 |
39.33 |
| 18 |
F |
18 |
hyperbilirubinaemia |
|
No |
670 |
5 |
11.7 |
61.56 |
| 19 |
M |
44 |
severe anaemia |
|
Yes |
0 |
7 |
6.9 |
13.68 |
| 20 |
F |
23 |
severe anaemia |
|
Yes |
264 |
8 |
6.4 |
6.84 |
| 21 |
M |
5 |
prostration |
|
No |
291 |
15 |
8.2 |
6.84 |
| 22 |
M |
21 |
hyperbilirubinaemia |
|
Yes |
832 |
7 |
9.7 |
102.6 |
| 23 |
M |
12 |
respiratory failure |
|
Yes |
0 |
6 |
7.8 |
15.39 |
| 24 |
F |
74 |
respiratory failure |
|
No |
325 |
5 |
11.7 |
29.07 |
| 25 |
M |
37 |
respiratory failure |
|
Yes |
0 |
10 |
7.1 |
17.10 |
| 26 |
F |
26 |
hyperbilirubinaemia |
|
No |
254 |
9 |
11.3 |
140.22 |
| 27 |
M |
53 |
hyperbilirubinaemia |
|
No |
45,833 |
6 |
11.8 |
59.85 |
| 28 |
F |
36 |
hyperbilirubinaemia |
|
No |
0 |
3 |
7.9 |
85.50 |
| 29 |
F |
15 |
severe anaemia |
|
Yes |
8,894 |
8 |
6.9 |
11.97 |
| 30 |
M |
22 |
hyperbilirubinaemia |
|
No |
3,054 |
7 |
15.1 |
73.53 |
| 31 | M | 25 | hyperbilirubinaemia | Yes | 27,954 | 3 | 15.0 | 138.51 | |
Severe anaemia was defined as haemoglobin levels below 7 g/dL for adults and below 5 g/dL for children and hyperbilirubinaemia by serum total bilirubins >51.3 μmol/L. Respiratory failure was defined as tachypnea, shortness of breath, mental confusion clinical signs of hypoxaemia (central and/or peripheral cyanosis). Previous treatment indicates participants who already started malaria therapy before the blood sample collection. *Total bilirubin was not measured in these individuals.