Table 5.
DDX39B polymorphisms (-22C > G and -348C > T) and complicated vivax malaria infections: second series of participants from Amazonas, Brazil
| |
Genotype |
χ2 |
Allele frequency |
χ2 | CC vs CG + GG χ2 | |||
|---|---|---|---|---|---|---|---|---|
| CC n (%) | CG n (%) | GG n (%) | C (%) | G (%) | ||||
|
DDX39B-22
polymorphism |
|
|
|
|
|
|
|
|
| Mild malaria (n = 69) |
5 (7.25) |
41 (59.42) |
23 (33.33) |
6.72 p = 0.0347 |
51 (36.96) |
87 (63.04) |
p = 0.0628* |
p = 0.0207* |
| Complicated malaria (n = 31) |
8 (25.80) |
16 (51.61) |
7 (22.58) |
32 (51.61) |
30 (48.39) |
|||
| |
Genotype |
|
Allele frequency |
|
CC
vs
TC + TT χ2 |
|||
| |
CC n (%) |
TC n (%) |
TT n (%) |
|
C (%) |
T (%) |
|
|
|
DDX39B-348
polymorphism |
|
|
|
|
|
|
|
|
| Mild malaria (n = 69) |
55 (79.71) |
14 (20.29) |
0 (0.00) |
p = 7,850*# | 124 (89.86) |
14 (10.14) |
p = 0.7965* | p = 7,850* |
| Complicated malaria (n = 31) | 26 (83.87) | 5 (16.13) | 0 (0.00) | 57 (91.93) | 5 (8.07) | |||
*In these cases, Fisher exact test was used. #Analysis excluded genotype TT. χ2: coefficient and P value measured using Chi-square test.