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. 2014 Apr 2;75(4):525–532. doi: 10.1002/ana.24114

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© 2014 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs 4.0 License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Fluorescence in situ hybridization (FISH) analysis at the SMN locus. FISH analysis in lymphoblastoid cell line #19441 with a 4 SMN1/0 SMN2 genotype shows signal amplification of both copies on chromosome 5 and not elsewhere.