. Author manuscript; available in PMC: 2014 Jul 28.

Published in final edited form as: J Med Genet. 2010 Jun 24;47(10):677–685. doi: 10.1136/jmg.2009.073775

Table 4.

Haplotype Frequency Estimates of the TCblR D’ Block^*

Haplotype	Controls	NTD cases	NTD mothers
GCTdelCGG	0.33	0.32	0.30
GGTdelCGG	0.24	0.24	0.24
AGCdelCGG	0.19	0.21	0.21
GGTdelCCG	0.10	0.10	0.11
GGCdelCGA	0.10	0.07	0.09
GCTdelTGG	0.02	0.03	0.02
GCTinsTGG	0.02	0.03	0.01
GGCdelCGG	0.01	0.01	0.01

p-value		0.3^**	1.0^**

The haplotype block consists of the following markers: rs4147651, rs7408841, rs2927707, E88del, rs2336573 (G220R), rs2227288, rsl73665.

^**

Result of permutation test for significant differences in haplotype frequencies in NTD cases vs. controls or NTD mothers vs. controls.