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Quantification of spinal cord cell infiltration, demyelination and axonal damage
| Treatment | Demyelination (%) a | APP + /mm 2a | CD3 + /mm 2a | Mac-3 + /mm 2a |
|---|---|---|---|---|
| Vehicle |
32.9 ± 6.0 |
45.4 ± 5.5 |
114.2 ± 59.2 |
480.8 ± 191.9 |
| Mepazine | 17.6 ± 7.5 | 29.2 ± 12.9 | 50.3 ± 22.5 | 246.5 ± 113.6 |
Samples were obtained from vehicle (n = 5) or mepazine (n = 6) treated animals. aResults are displayed as mean ± SEM.
