Table 4.
Description of the different variables assessed in animals with different courses of disease
Variable |
Peracute |
Acute |
Subclinical |
Uninfected |
|
---|---|---|---|---|---|
(n = 9) | (n = 31) | (n = 12) | (n = 9) | ||
Clinical signs |
Mortality prior to the end of the experiment (%)* |
9 (100)a |
0 (0)b |
0(0)b |
0 (0)b |
Fever at least one day (%)* |
9 (100)a |
29 (93.5)a |
6 (50)b |
2 (22.2)b |
|
Clinical score higher than 0 (%)* |
9 (100)a |
28 (90.3)a |
2 (16.6)b |
3 (33.3)b |
|
Mean clinical score (±SD) |
1.88 (±0.80)a |
1.32 (±0.70)a |
0.16 (±0.4)b |
0.44 (±0.8)b |
|
Inappetence at least one day (%)* |
9 (100)a |
21(67.7)b |
3 (25.0)c |
2 (22.2)c |
|
Production |
Mean ADG (±SD) (kg/d) |
-1.91 (±0.83)a |
0.47 (±0.4)b |
0.83 (±0.2)c |
0.9 (±0.2)c |
Diagnostic | App-like lesions (%)* |
9 (100)a |
30 (96.7)a |
0 (0)b |
0 (0)b |
App isolation (%)* |
9 (100)a |
30 (96.7)a |
3 (25)b |
0 (0)b |
|
PCR detection in tonsil (%)* |
8 (88.8)a |
18 (58.0)a |
10 (83.3)a |
0 (0)b |
|
PCR detection in bronchial lymph node (%)* |
5 (55.5)a |
14 (45.1)a |
4 (33.3)a |
0 (0)b |
|
Seropositivity to App at death/necropsy* |
0 (0)a |
16 (51.6)b,c |
3 (25.0)a,c |
0 (0)a |
|
Mean SPES (Min-Max) |
3.88 (3- 4)a |
2.09 (1-4)b |
0c |
0c |
|
Mean LLS (Min-Max) |
17.57 (10.71-31.4)a |
5.17 (0.26-20.94)b |
0c |
0c |
|
Mean IA (±SD) |
53.3 (±16.11)a |
17.29 (±14.00)b |
0c |
0c |
|
Ratio LW/BW (±SD) | 0.91(±0. 00)a,b** | 1.27 (±0.54)b | 0.88 (±0.21)a | 0.96a,b (±0.18) |
Different letter in superscript means statistically significant differences within a given variable (p < 0.05). % = percentage; Min = minim; Max = Maximum; SD = standard deviation; *Number of animals showing or being positive by the corresponding parameter. **Data available only from one animal.