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Correlation between the incidence of mesothelioma in rats and in vitro cytotoxicity or initiation of abnormal anaphase/telophase in cultures of rat pleural mesothelial cells * [[87]]
| |
Probability of mesothelioma induction based on: |
|
|---|---|---|
| Metric | Cytotoxicity (IC 75 ) | Abnormal mitosis |
| Weight |
0.16 |
0.27 |
| Total fibers |
0.56 |
0.14 |
| “Stanton” fibers |
0.84 |
0.0075 |
| “Pott” fibers |
ND |
0.14 |
| Fibers > 4 μm in length | ND | 0.25 |
*Rank Spearman test.
ND: not determined.
