Table 1.
Demographics-primary analysis n (%)
| Included (n = 65) | Excluded (n = 117) | P value | |
| Age (yr) | 12.98 ± 2.8 | 13.4 ± 2.9 | NS |
| Gender | |||
| Male | 39 (60.0) | 65 (55.6) | NS |
| Female | 26 (40.0) | 52 (44.4) | |
| Disease duration | |||
| < 12 mo | |||
| > 12 mo | 59 (90.7) | 100 (85.5) | NS |
| 6 (9.2) | 17 (14.5) | ||
| Race | |||
| Caucasian | 52 (80.0) | 102 (87.2) | NS |
| Disease location | |||
| Upper | 37 (56.9) | 79 (67.5) | NS |
| Ileal | 49 (75.4) | 91 (77.9) | NS |
| Colonic | 54 (83.1) | 97 (82.9) | NS |
| Thiopurine | |||
| 6MP | 42 (64.6) | 87 (77.0) | NS |
| AZA | 23 (35.4) | 26 (23.0) | |
| PGA | |||
| Remission | 7 (10.8) | 5 (4.4) | NS |
| Mild | 22 (33.8) | 41 (36.3) | |
| Moderate | 31 (47.7) | 58 (51.3) | |
| Severe | 5 (7.7) | 9 (8.0) | |
| Mean initiation dosage | |||
| (mg/kg) | 0.89 ± 0.31 | 1.06 ± 0.37 | 0.002 |
| 6TG level | 258 ± 147 | 231 ± 161 | NS |
| (pmole/8 × 108 RBC) | (n = 31) | (n = 55) |
NS: No significant.