Table 1.
Sensitivities and specificities of various studies that took blood samples n (%)
| Source | Method | Marker | Sensitivity | Specificity | Ref. |
| Serum | MSP | CDKN2A (p16) | 14/52 (27) | 44/44 (100) | [32] |
| Serum | RT-PCR | CEA | 51/121 (42) | 27/33 (82) | [56] |
| Serum | RT-PCR | CK20 | 22/99 (22) | 150/150 (100) | [38] |
| Serum | qPCR | miR-92 | 80/90 (89) | 35/50 (70) | [84] |
| Serum | CellSearch | EpCAM | 20/74 (27) | 228/246 (93) | [88] |
| Serum | CLIA | CEA | 188/429 (44) | 184/201 (92) | [112] |
MSP: Methylation-specific polymerase chain reaction; qPCR: Quantitative reverse transcription polymerase chain reaction (RT-PCR); CLIA: Chemiluminescence immunoassay; CEA: Carcinoembryonic antigen; CK20: Cytokeratin 20; EpCAM: Epithelial cell adhesion molecule.