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. 2014 Jul 21;20(27):8998–9016. doi: 10.3748/wjg.v20.i27.8998

Table 4.

Incidence of hepatocellular carcinoma before and after the introduction of universal vaccination for hepatitis B virus

Ref. Country Subjects Year of the introduction of universal vaccination Annual incidence of HCC cases per 100000 population
Before vaccination program Year After vaccination program Year
102 United States (Alaska) Under 20 yr of age 1984 3 1984-1988 0 1995-1999
109 Taiwan 6-14 yr of age 1984 0.7 1981-1986 0.36 1990-1994
109 Taiwan 6-9 yr of age 1984 0.52 1974-1984 0.13 1984-1986

HCC: Hepatocellular carcinoma.