Table 3.
Predictors of survival on multivariate analysis using a Cox regression model in patients with spontaneous rupture of hepatocellular carcinoma
| Variable | Overall survival |
Disease-free survival |
||||
| HR | 95%CI | P value | HR | 95%CI | P value | |
| Age | 1.01 | 0.99-1.03 | 0.348 | 1.02 | 0.99-1.05 | 0.097 |
| Liver cirrhosis (yes vs no) | 1.05 | 0.55-2.03 | 0.878 | 1.29 | 0.54-3.09 | 0.566 |
| BCLC stage (stage A vs stage B) | 1.35 | 0.60-3.06 | 0.470 | 1.13 | 0.41-3.07 | 0.817 |
| Tumor size | 0.96 | 0.88-1.06 | 0.456 | 0.92 | 0.81-1.05 | 0.235 |
| Tumor location | 1.02 | 0.59-1.76 | 0.936 | 1.24 | 0.64-2.42 | 0.524 |
| Satellite nodule(s) (yes vs no) | 0.77 | 0.46-1.27 | 0.299 | 0.76 | 0.39-1.47 | 0.413 |
| Blood loss | 1.00 | 1.00-1.00 | 0.085 | 1.00 | 1.00-1.00 | 0.940 |
| Blood transfusion (yes vs no) | 1.00 | 0.51-1.98 | 0.994 | 1.12 | 0.49-2.59 | 0.788 |
| Radical resection (yes vs no) | 0.32 | 0.08-0.61 | 0.015 | 0.12 | 0.01-0.73 | 0.002 |
HCC: Hepatocellular carcinoma; HR: Hazard ratio; CI: Confidence interval; BCLC: Barcelona clinic liver cancer.