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. 2014 Jul 21;20(27):8796–8806. doi: 10.3748/wjg.v20.i27.8796

Table 2.

Response rates for lubiprostone 12 wk phase III irritable bowel syndrome with constipation studies

Lubiprostone Placebo P value
Overall responder 17.90% 10.10% 0.001
Month 1 10.80% 7.50% 0.078
Month 2 18.20% 11.40% 0.003
Month 3 22.00% 14.50% 0.003