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. 2014 Jul 21;20(27):9178–9184. doi: 10.3748/wjg.v20.i27.9178

Table 1.

Definitions of phases of persistent hepatitis B virus infection

Phase HBV-DNA (IU/mL) HBeAg status ALT (U/L) Liver imaging
IT > 107 + ≤ ULN No cirrhosis
IC > 2000 + ≥ 2ULN No cirrhosis
ENH > 2000 - ≥ 2ULN No cirrhosis
LR < 2000 - ≤ ULN No cirrhosis
LC Any +/- Any Cirrhosis

IT: Immune tolerance phase; IC: Immune clearance phase; ENH: HBeAg(-) hepatitis; LR: Low-replicative; LC: Liver cirrhosis induced by hepatitis B virus; HBeAg: Hepatitis B e antigen; HBV: Hepatitis B virus; ULN: Upper limit of normal; “+”: Positive; “-”: Negative.