Table 2.
Baseline population characteristics
| Immune tolerant | Immune clearance | HBeAg negative hepatitis | Low replicative | Liver cirrhosis | P value | |
| HBeAg status | Positive | Positive | Negative | Negative | Positive/negative | |
| Sex M/F | 60/48 | 127/34 | 124/25 | 95/40 | 50/20 | < 0.001 |
| Age (yr) | 26 (18-44) | 29 (18-45) | 41 (22-60) | 39 (22-65) | 49 (26-65) | < 0.001 |
| ALT (U/L) | 25 (9-40) | 188 (80-1322) | 40 (80-3755) | 23 (17-39) | 45 (9-341) | < 0.001 |
| AST (U/L) | 20 (6-36) | 100 (7-1063) | 228 (20-2136) | 14 (9-38) | 49 (10-302) | < 0.001 |
| HBsAg (log10 IU/mL) | 4.85 (3.97-5.15) | 4.36 (3.08-5.25) | 2.95 (0.82-4.89) | 3.18 (2.53-3.60) | 2.69 (2.20-4.04) | < 0.001 |
| HBV DNA (log10 IU/mL) | 8.50 (7.12-9.49) | 7.93 (3.93-9.23) | 5.73 (3.3-9.28) | 2.64 (2.18-3.30) | 4.68 (3.28-8.75) | < 0.001 |
| Genotype | ||||||
| B/C | 60/48 | 83/78 | 86/62 | 74/61 | 37/33 | 0.006 |
HBsAg: Hepatitis B s antigen; HBeAg: Hepatitis B e antigen; HBV: Hepatitis B virus; ALT: Alanine transaminase; AST: Aspartate aminotransferase.