Table 4.

Dissociable brain activity for negative vs. neutral stimuli by arousal levels in young and older adults.

Contrast	Brain region	BA	H	Voxels	Talairach coordinates			t
					x	y	z
YOUNG > OLDER
High arousal (NegHi vs. NeuAll)
Cuneus		18	R	26	12	−85	19	4.26
					8	−92	19	3.71
Precuneus		19	R	12	28	−60	36	3.94
Middle temporal gyrus		19	R	21	48	−61	14	3.85
Cingulate gyrus		32	L	17	−4	17	32	3.69
Postcentral gyrus		2	R	10	51	−21	42	3.66
Middle temporal gyrus		19	L	18	−44	−61	14	3.60
Middle temporal gyrus		37			−51	−62	3	2.83
Medium arousal (NegMed vs. NeuAll)
Middle occipital gyrus		18	L	21	−32	−89	4	3.47
					−24	−89	15	3.38
Low arousal (NegLo vs. NeuAll)
Amygdala		34	L	11	−20	−1	−10	2.49*
					−32	−5	−17	2.10*
Amygdala		28	R	18	16	−4	−10	2.44*
		34			28	3	−14	1.96*
Inferior frontal gyrus		47	R	34	44	11	−4	4.81
Superior temporal gyrus		41	R	13	40	−35	9	4.02
					48	−31	5	3.17
					40	−38	16	2.82
Middle temporal gyrus		39	R	23	48	−61	21	3.85
					44	−54	14	3.31
					48	−62	10	2.99
Superior frontal gyrus		9	R	26	40	40	31	3.79
					16	52	38	3.78
					4	56	38	3.67
Superior frontal gyrus		9	L	22	−28	52	34	3.77
					−12	52	38	3.62
Middle occipital gyrus		19	L	14	−28	−77	11	3.75
					−32	−85	8	3.43
					−24	−89	15	3.09
Inferior frontal gyrus		47	L	20	−48	42	−9	3.75
					−51	30	−5	2.94
					−55	35	2	2.86
Middle frontal gyrus		8	R	32	36	22	47	3.68
					48	21	39	3.67
					32	6	58	3.25
Superior temporal gyrus		38	L	40	−44	11	−14	3.64
					−40	23	−11	3.47
					−51	7	−7	3.32
OLDER > YOUNG
Low arousal (NegLo vs. NeuAll)
Anterior cingulate gyrus		32	L	39	−16	36	13	4.22
					−12	43	−2	2.42
		32	R	8	8	40	16	1.88

BA, Brodmann's area; H, Hemisphere. A threshold of p < 0.005 (uncorrected) was used. Bolded t-values indicate the voxels surviving a cluster-level threshold of p < 0.05 (FDR-corrected).

^*Denotes significant difference at p < 0.05 (uncorrected).