Table 4.
Relative risk of cancer in Peutz-Jeghers syndrome
| |
Resta et al.
[41] |
Giardiello et al.
[42] |
|---|---|---|
| Study design | Retrospective cohort study | Meta-analysis |
| Any cancer |
15.1 (CI 10.5-21.2) |
15.2 |
| Breast |
12.5 (CI 5.1-26.0) |
15.2 |
| Cervix |
55.6 (CI 17.7-134.0) |
1.5 |
| Gynaecological cancers |
27.7 (CI 11.3-57.6) |
NA |
| Colorectal cancer |
13.5 (CI 4.3-32-5) |
84.0 (Colon) |
| Pancreas |
139.7 (CI 61.1-276.4) |
132 |
| Gastrointestinal cancer |
126.2 (CI 73.3-203.4) |
NA |
| Ovary |
NA |
27.0 |
| Uterus |
NA |
16.0 |
| Testes |
NA |
4.5 |
| Lung |
NA |
17.0 |
| Small intestines |
NA |
520.0 |
| Stomach |
NA |
213.0 |
| Oesophagus | NA | 57.0 |