Table 2.
Clinical performance characteristics compared to the modified gold standard
| Method |
Clinical Parameters* |
|||
|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | Kappa | False positivity rate (%) | |
| Real-time RT-PCR |
100.0 (91.5 – 100.0) |
100.0 (98.2 – 100.0) |
1.00 (0.90 – 1.00) |
0.00 |
| EP-JV |
71.9 (58.6 – 71.9) |
98.1 (95.3 – 99.5) |
0.76 (0.58 – 0.84) |
1.99 |
| EP-SR |
62.5 (48.4 – 71.7) |
96.8 (93.8 – 98.7) |
0.65 (0.46 – 0.77) |
3.36 |
| EP-JV and EP-SR | 75.0 (60.3 – 85.5) | 94.8 (91.7 – 97.0) | 0.70 (0.52 – 0.82) | 5.47 |
*When applicable, 95% confidence intervals are indicated in parentheses.