Table 1.

Differentially expressed genes in strain EC-2 ( P  < 0.05, |log ₂ FC| ≥ 1.0)

Locus tag	Gene	Putative function	COG description 1	Log 2 FC 2
Up-regulated genes
SO_0817	metR	Transcriptional activator protein MetR	Transcription	3.33
SO_0818	metE	5-Methyltetrahydropteroyltriglutamate-homocysteine methyltransferase	Amino acid transport and metabolism	6.49
SO_1101	luxS	S-Ribosylhomocysteinase	Signal transduction mechanisms	1.65
SO_1860	–	Response regulator	Signal transduction mechanisms, Transcription	5.97
SO_2404	aroA	3-Phosphoshikimate 1-carboxyvinyltransferase	Amino acid transport and metabolism	1.17
SO_3471	glyA	Serine hydroxymethyltransferase	Amino acid transport and metabolism	1.55
SO_3534	murJ	Peptidoglycan lipid II flippase	General function prediction only	1.17
SO_4189	–	Hypothetical protein SO_4189	Carbohydrate transport and metabolism	1.04
SO_4233	leuD	Isopropylmalate isomerase small subunit	Amino acid transport and metabolism	1.69
SO_4596	–	Copper-transporting ATPase domain-containing protein	–	2.09
SO_4731	add	Adenosine deaminase	Nucleotide transport and metabolism	1.42
Down-regulated genes
SO_0351	–	LuxR family DNA-binding response regulator	Signal transduction mechanisms, Transcription	-1.04
SO_1861	uvrC	Excinuclease ABC subunit C	Replication, recombination and repair	-1.30
SO_2005	–	DksA-type zinc finger protein	Signal transduction mechanisms	-1.16
SO_2906	–	Hypothetical protein SO_2906	Inorganic ion transport and metabolism	-1.92
SO_2945	–	Lambda phage tail fiber protein	–	-1.45
SO_2946	–	Lambda phage protein with carbohydrate-binding module	–	-1.10
SO_2953	H	Prophage LambdaSo, tail length tape meausure protein	Function unknown	-1.48
SO_2954	–	Hypothetical protein SO_2954	–	-1.53
SO_2955	–	Lambda phage minor tail protein G	–	-1.62
SO_2956	–	Prophage LambdaSo, major tail protein V, putative	–	-1.60
SO_2957	–	Lambda phage protein of unknown function	–	-1.35
SO_2965	–	Prophage LambdaSo, HK97 family portal protein	Function unknown	-1.24
SO_2968	–	Phage terminase small subunit	Replication, recombination and repair	-1.03
SO_2969	–	Prophage LambdaSo, holin, putative	Defense mechanisms	-1.24
SO_4564	–	TonB2 protein, putative	Cell wall/membrane/envelope biogenesis	-1.15

¹Functional categorization by COG.

²Log₂-transformed fold change (EC-2/∆SO_1860).