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. 2014 Jul 5;15:80. doi: 10.1186/1471-2156-15-80

Table 3.

Hardy Weinberg equilibrium and LD variance for the three EAAT2 SNPs using pyrosequencing or SSCP

  Pyrosequencing SSCP
 
Hardy-Weinberg
for -168
p > 0.99
N/A
for -181
p = 0.0188
p = 0.4063
for -200
p = 0.0256
p = 0.3325
 
Lewontin’s D’
-168 and -181
0.49
N/A
-168 and -200
1
N/A
-181 and -200
0.94
1
 
r 2
-168 and -181
0
N/A
-168 and -200
0
N/A
-181 and -200 0.79 0.99

Lewontin’s D’ and r2 both give ordinal measures of Linkage Disequilibrium (LD). Please note only one mutation was found at -168 making interpretation difficult for these associations.