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. Author manuscript; available in PMC: 2014 Jul 28.
Published in final edited form as: Circulation. 2012 Aug 24;126(15):1907–1916. doi: 10.1161/CIRCULATIONAHA.112.106245

Table 1.

Clinical characteristics of the BMPR2 mutation carriers

AMCs (n=47) UMCs (n=35) P value
Females 35 (74.5) 15 (48.4) 0.029
Age, yr
    At diagnosis 36.4 ± 14.1 n/a n/a
    At present or at death n/a 60.5 ± 17.3 n/a
NMD+ mutations 27 20
NMD− mutations 20 15
Baseline hemodynamic data at diagnosis, mean
    Right atrial pressure, mmHg 10.3 ± 6.0 n/a
    Mean PAP, mmHg 61.3 ± 12.0 n/a
    Cardiac index, L•min•m−2 1.90 ± 0.73 n/a
    Indexed PVR, U•m2 19.3 ± 12.7 n/a

Abbreviations: AMC, affected mutation carrier with HPAH; UMC, unaffected mutation carrier; NMD, nonsense mediated decay; PAP, pulmonary artery pressure; CI, cardiac index; PVR, pulmonary vascular resistance; n/a, not available

Data are presented as n (%) or mean ±SD, unless otherwise stated. A chi square test was used for P value calculation.