Table 3.
Patient and Disease Characteristics for Matched Patients[*]
| Variable | SBRT (N=56) |
Surgery (N=56) |
p-value[1] |
|---|---|---|---|
| Age, years (mean ± SD) | 70.7 ± 10.6 | 70.0 ± 8.1 | 0.6496 |
| Age>75 years (%) | 20 (35.7) | 16 (28.6) | 0.4183 |
| Male (%) | 29 (51.8) | 32 (57.1) | 0.5692 |
| Race[2] | 0.3207 | ||
| White | 49 (89.1) | 53 (94.6) | |
| Black | 6 (10.9) | 3 (5.4) | |
| Weight (lb) [3] | 175.6 ± 54.5 | 164.3 ± 44.1 | 0.3355 |
| T2 (%) | 16 (28.6) | 24 (42.9) | 0.1147 |
| CM Score (%) | 0.5702 | ||
| 2 – 3 | 31 (55.4) | 28 (50.0) | |
| Smoking[2] | 0.2060 | ||
| Yes | 51 (92.7) | 55 (98.2) | |
| No | 4 (7.3) | 1 (1.8) | |
| Hypertension[2] | 0.6989 | ||
| Yes | 33 (62.3) | 6 (75.0) | |
| No | 20 (37.7) | 2 (25.0) | |
| Size of Tumor | 2.5 ± 1.1 | 3.0 ± 1.6 | 0.3095 |
| Location of Tumor | 0.3408 | ||
| Peripheral | 49 (87.5) | 52 (92.9) | |
| Central | 7 (12.5) | 4 (7.1) | |
| FEV1 (mean ± SD) [3] | 1.6 ± 0.7 | 1.6 ± 0.6 | 0.6156 |
| FEV 1(%) (mean ± SD) | 64 ± 24 | 62 ± 18 | 0.8522 |
| DLCO (mean ± SD) [3] | 11.6 ± 5.3 | 14.3 ± 4.8 | 0.0020 |
| DLCO (%) (mean ± SD) [3] | 55 ± 20 | 73 ± 27 | 0.0001 |
| Surgery Procedure Type (%) | |||
| Bilobectomy | NA | 1 (1.8) | |
| Lobectomy | 44 (78.6) | ||
| Pneumonectomy | 0 | ||
| Segmentectomy | 6 (10.7) | ||
| Wedge | 5 (8.9) | ||
[*]
Age, comobidity score, FEV 1 (%), tumor location, and tumor size were used for propensity score estimation. c-statistics is 0.824. The matched pair is found using a caliper technique with a standard deviation defined as 0.075 of the estimated propensity score for both groups.
Abbreviations: SD, standard deviation; NA, not applicable.
[1]
Chi-square or Fisher Exact test for categorical variable; Kruskal-Wallis Test for continuous variable.
[2]
The denominator for the percentages is the sum of patients across all categories in the SBRT or Surgery group, respectively, excluding missing values.
[3]
Missing values;