Table 2.

Withdrawal Rates in the PRESENT Study (Intention to Treat Population)

Reason for dropping out	Misoprostol (n=237)	Rebamipide (n=242)	Total (n=479)	p-value*
AEs	10	4	14
Poor compliance with the protocol	1	3	4
Consent withdrawal†	33	15	48
Other	0	3	3
Total, no. (%)	44 (18.6)	25 (10.3)	69 (14.4)	0.0103

AE, adverse event.

^*Chi-squared test;

^†Intractable gastrointestinal symptoms and insufficient pain control.