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. 2014 Jul 1;8(4):452–458. doi: 10.5009/gnl.2014.8.4.452

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Copyright © 2014 by The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — Microscopic and immunohistochemical features of case 1. (A) The mass shows a well-defined border with an expanding growth pattern (H&E stain, ×40). (B) The tumor cells of the outer nodule show a trabecular pattern of one- or two-cell thickness with mild nuclear atypia (H&E stain, ×200). (C) Several abnormally shaped blood vessels with infiltration of mononuclear inflammatory cells are noted within the tumor (H&E stain, ×200). (D) The tumor cells of the inner nodule show stromal invasion (H&E stain, ×200). (E, F) The tumor cells of the outer and inner nodules show diffuse and strong cytoplasmic expression of serum amyloid protein A (E) and glutamine synthetase (F) (×200). (G) The tumor cells of the outer and inner nodules show diffuse nuclear expression of β-catenin (×400). (H) The tumor cells of the inner nodule show the focal expression of heat shock protein 70 (×200).