Table 1. Potential Prenatal Testing Categories.
Type of information | Does it inform reproductive decision-making for current pregnancy? | Might the future child have an interest in not knowing the information? | Could it provide immediate benefit to the future child? |
---|---|---|---|
Variants of unknown significance (genetic variations whose association with disease risk is unknown) | No | Yes | No |
Nonmedical genetic markers (genetic variations that have no health-related significance) | No | Yes | No |
Carrier status (possession of genetic variations that do not cause illness in the carrier but might contribute to illness in the carrier's offspring) | No | Yes | No |
Susceptibility genes (genes with variants that indicate increased likelihood for developing a condition) | Sometimes | Yes | No |
Late onset genetic conditions (highly penetrant genetic conditions that display no symptoms until late in life) | Sometimes | Yes | No |
Medical conditions found by current prenatal genetic tests (conditions with 100 percent penetrance that seriously affect health and quality of life throughout the life cycle) | Yes | NA | Sometimes |