Table 3.
Concentration of ATS and DHA in commercial drugs determined with dipsticks and HPLC
| Drug names | Lot no. | The claimed content (mg/pill, tube) | Theoretical a.i. content a (mg/mL) | Measured content by dipsticks (mg/mL) | Measured content by HPLC b (mg/mL) |
|---|---|---|---|---|---|
| ATS tablets |
040502 |
50 |
2.00 |
2-4 |
2.33 ± 0.00c |
| AS100801 |
50 |
2.00 |
2-4 |
2.12 ± 0.01c |
|
| ATS for injection |
LA110102 |
60 |
2.00 |
2-4 |
2.12 ± 0.01c |
| DHA and piperaquine phosphate tablets |
030211 |
40 |
2.00 |
1-2.5 |
2.04 ± 0.03c |
| 010710 |
40 |
2.00 |
1-2.5 |
2.03 ± 0.01c |
|
| 020807 |
40 |
2.00 |
1-2.5 |
2.02 ± 0.00c |
|
| Artesun-Plus |
SH120707 |
100 |
2.00 |
2-4 |
2.21 ± 0.01 |
| Artecospe | S130304 | 100 | 2.00 | 2-4 | 2.08 ± 0.01 |
aTheoretical content of active ingredients according to the values shown on the label;
bData represent means of triplicates ± SD.
cData from Wang et al. 2012.