Table 2.

IRR for diabetes according to CES-D score categories and use of antidepressant medication in the BWHS, 1999–2011

	CES-D score categories				Antidepressant use
	<16	16–22	23–32	≥33	No	Yes
All BMI
Cases/person-years	2,306/261,795	549/52,538	339/31,365	178/13,709	3,079/340,419	293/18,988
IRR
Basic multivariate*	1.00 (reference)	1.23 (1.12–1.35)	1.26 (1.12–1.41)	1.45 (1.24–1.69)	1.00 (reference)	1.43 (1.26–1.62)
+Lifestyle factors†	1.00 (reference)	1.18 (1.07–1.30)	1.17 (1.04–1.32)	1.31 (1.12–1.53)	1.00 (reference)	1.35 (1.19–1.53)
+BMI	1.00 (reference)	1.11 (1.01–1.22)	1.08 (0.96–1.22)	1.22 (1.04–1.43)	1.00 (reference)	1.26 (1.11–1.43)
BMI ≥30 kg/m2
Cases/person-years	1,550/93,203	380/21,932	260/13,871	137/6,357	2,105/126,564	222/8,799
IRR‡	1.00 (reference)	1.06 (0.95–1.19)	1.10 (0.96–1.26)	1.24 (1.03–1.48)	1.00 (reference)	1.26 (1.09–1.46)

*Basic covariates: age, questionnaire cycle, healthcare utilization, family history of diabetes, and years of education.

†Lifestyle factors: vigorous activity levels, daily hours of television watching, caloric intake, smoking, and alcohol consumption.

‡IRRs adjusted for all basic covariates + lifestyle factors + continuous BMI.