Table 3.
IRR for diabetes according to combined categories of CES-D score and use of antidepressant medication in the BWHS, 1999–2011
| CES-D score categories |
||||||||
|---|---|---|---|---|---|---|---|---|
| <16 | 16–22 | 23–32 | ≥33 | |||||
| On antidepressants |
No |
Yes |
No |
Yes |
No |
Yes |
No |
Yes |
| All BMI | ||||||||
| Cases/person-years | 2,191/252,524 | 115/9,271 | 477/48,776 | 72/3,762 | 284/28,052 | 55/3,313 | 127/11,067 | 51/2,642 |
| IRR | ||||||||
| Basic multivariate* | 1.00 (reference) | 1.30 (1.08–1.57) | 1.19 (1.08–1.32) | 2.07 (1.64–2.63) | 1.25 (1.10–1.42) | 1.80 (1.38–2.36) | 1.45 (1.21–1.74) | 2.01 (1.52–2.66) |
| +Lifestyle factors† | 1.00 (reference) | 1.20 (1.00–1.45) | 1.14 (1.03–1.26) | 1.89 (1.50–2.40) | 1.16 (1.02–1.32) | 1.61 (1.23–2.11) | 1.30 (1.09–1.56) | 1.74 (1.32–2.30) |
| +BMI | 1.00 (reference) | 1.13 (0.94–1.37) | 1.08 (0.97–1.19) | 1.64 (1.30–2.08) | 1.08 (0.95–1.23) | 1.33 (1.02–1.75) | 1.20 (1.00–1.44) | 1.58 (1.19–2.09) |
| BMI ≥30 kg/m2 | ||||||||
| Cases/person-years | 1,466/89,243 | 84/3,960 | 323/20,101 | 57/1,831 | 220/12,158 | 40/1,713 | 96/5,062 | 41/1,295 |
| IRR‡ | 1.00 (reference) | 1.14 (0.92–1.43) | 1.02 (0.91–1.15) | 1.67 (1.28–2.18) | 1.12 (0.97–1.30) | 1.21 (0.88–1.66) | 1.19 (0.97–1.47) | 1.67 (1.22–2.29) |
*Basic covariates: age, questionnaire cycle, healthcare utilization, family history of diabetes, and years of education.
†Lifestyle factors: vigorous activity levels, daily hours of television watching, caloric intake, smoking, and alcohol consumption.
‡IRRs adjusted for all basic covariates + lifestyle factors + continuous BMI.