Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Mar 19;10:22. doi: 10.1186/1744-8069-10-22

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Bali et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Only a small fraction of miRNAs were regulated differentially by SNL nerve injury in HA compared to LA rats. In this “volcano plot” each dot represents one of the 284 miRNAs detected in the DRGs studied, with the degree of differential regulation (diff-reg, LA-HA) plotted against the statistical significance of the diff-reg (FDR corrected q-values, given as -log₁₀). LA-HA was calculated as the difference between the mean log2 ratios of LA_SNL/LA_sham and HA_SNLl/HA_sham (average of pool values). Data used for the plot excluded outlier pool HA_SNL1. miRs 125b-5p, 30d-5p and 379-5p are indicated with arrows. The other significantly diff-reg miRNAs were expressed at low abundance (Table 1).