Table 1.
Mature miRNAs that underwent significant differential up- or down-regulation following SNL nerve injury in HA vs. LA rats
|
miRNA identifier name |
Mean RPM (sham pools) |
Mean RPM (SNL pools) |
SNL-reg
subtraction method (SNL/sham fold-change) |
diff-reg
|
qFDR
|
chr. # |
|||
|---|---|---|---|---|---|---|---|---|---|
| HA | LA | HA | LA | HA | LA | HA-LA | HA-LA | ||
|
subtraction method, all pools | |||||||||
|
rno-miR-30d-5p |
9,187 |
11,047 |
8,140 |
11,168 |
−0.121 (−1.129) |
0.011 (1.011) |
−0.132 (0.297) |
<0.001 |
7 |
| rno-miR-378b |
51.6 |
47.1 |
58.6 |
33.7 |
0.125 (1.136) |
−0.331 (−1.398) |
0.457 (0.533) |
<0.001 |
5 |
| rno-miR-322-3p |
30.7 |
29.4 |
20.8 |
32.8 |
−0.384 (−1.476) |
0.109 (1.116) |
−0.494 (0.592) |
<0.001 |
X |
|
added by log2 ratio method or randomization *, all pools | |||||||||
| rno-miR-493-3p |
79.8 |
66.3 |
87.9 |
91.0 |
0.138 (1.102) |
0.455 (1.373) |
0.317 (0.271) |
<0.001 |
6 |
| rno-miR-1839-5p * |
112.1 |
108.9 |
100.3 |
129.1 |
−0.110 (−1.118) |
0.168 (1.185) |
−0.278 (.303) |
<0.05 |
1 |
|
added by HA_SNL1 pool exclusion |
|
|
|
|
|
|
|
||
|
rno-miR-125b-5p |
3,758 |
2,537 |
2,718 |
2,398 |
−0.321 (−1.383) |
−0.056 (−1.058) |
−0.265 (0.325) |
0.002 |
8 |
|
rno-miR-379-5p |
201.9 |
187.5 |
188.6 |
231.6 |
−0.068 (−1.071) |
0.210 1.235 |
−0.278 (0.306) |
0.04 |
6 |
| rno-miR-369-3p |
12.0 |
13.6 |
16.9 |
15.8 |
0.337 (1.408) |
0.148 (1.162) |
0.189 (0.246) |
0.03 |
6 |
| rno-let-7f-2-3p |
11.7 |
8.1 |
10.4 |
12.8 |
−0.119 (−1.125) |
0.448 (1.580) |
−0.567 (0.705) |
0.03 |
X |
| rno-miR-340-3p |
8.9 |
11.5 |
12.6 |
9.3 |
0.346 (1.416) |
−0.215 (−1.237) |
0.561 (0.653) |
0.03 |
10 |
| rno-miR-6331 | 15.0 | 10.5 | 11.8 | 13.2 | −0.241 (−1.271) | 0.226 (1.257) | −0.467 (0.528) | 0.05 | 6 |
Relatively abundant transcripts are in bold font.