Table 2.
Central Nervous System (CNS) structural abnormalities in our cohort of patients
| CNS structural abnormalities: type | MRI/p.m.* | eco/CT | Tot. N° (%)a | Tot. N° (%)b |
|---|---|---|---|---|
|
Agenesis/hypoplasia of the Corpus Callosum (ACC) |
34/42 (80.95) |
11/29 (37.93) |
45/71 (63.38) |
45/117(38.46) |
|
Intracerebral arachnoid cysts |
19/42 (45.24) |
6/29 (20.69) |
25/71 (35.21) |
25/117(21.36) |
|
Malformations of cortical development (MCDs) |
22/42 (52.38) |
1/29 (3.45) |
23/71 (32.39) |
23/117(19.65) |
|
Cerebellar developmental anomalies (CDAs) |
18/42 (42.86) |
2/29 (6.9) |
20/71 (28.17) |
20/117(17.09) |
|
- Dandy-Walker Malformation (DWM) |
5/42 (11.90) |
0/29 (0) |
5/71 (7.04) |
5/117(4.27) |
|
Cerebral atrophy/hypoplasia |
5/42 (11.90) |
4/29 (13.79) |
9/71 (12.68) |
9/117(7.69) |
|
Hydrocephalus/ventriculomegaly |
6/42 (14.29) |
2/29 (6.9) |
8/71 (11.27) |
8/117(6.83) |
|
Porencephaly |
1/42 (2.38) |
2/29 (6.9) |
3/71 (4.22) |
3/117(2.56) |
|
Brain stem anomalies |
2/42 (4.76) |
0/29 (0) |
2/71 (2.82) |
2/117(1.7) |
|
Hypothalamic hamartoma |
1/42 (2.38) |
0/29 (0) |
1/71 (1.41) |
1/117(0.85) |
| Total | 42/42 (100) | 21/29 (72.41) | 63/71 (88.73) | 63/117(53.84) |
*p.m. : post-mortem evaluation.
apercentages calculated on the total number of cases displaying CNS involvement.
bpercentages calculated on the entire cohort of cases.