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. 2014 Jul;53(4):387–391.

Table 1.

Pharmacokinetic data for Bup IR and Bup SR Lab

Parameter Unit Bup IR Bup SR Lab
Dose mg/kg 0.03 0.05 0.1 2 0.3 1.2
AUClast h × ng/mL 2.2 ± 0.6 5.6 ± 2.7 19.1 ± 5.0 82.0 ± 18.2 20.1 ± 5.7 62.9 ± 11.6
Tmax h 1 1 3 1 6 0.5
Cmax ng/mL 0.5 ± 0.4 0.5 ± 0.4 1.3 ± 1.4 20.2 ± 11.9 0.8 ± 0.7 5.0 ± 2.3