Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Allelic c.677T>A and c.700C>T mutations in families to probands diagnosed with arRP of Bothnia dystrophy. Detection of both mutations was done by PCR-RFLP. a. Pedigree charts of 5 families where filled symbols indicate affected individuals, while empty symbols indicate unaffected. b. c.700C>T mutation abolishes a MspI restriction site and results in one fragment of 213 bp. c. c.677T>A mutation abolishes a NspI restriction site and results in one fragment of 310 bp
