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(A–D) MIP-133 induces IL-8 (A), IL-6 (B), IL-1β (C), and IFN-γ (D) protein expression in HCE cells. HCE cells were exposed to MIP-133 at doses of 7.5, 15, and 50 μg/mL for 6, 12, and 24 hours. Supernatants were collected from harvested cells and subjected to cytokine-specific ELISA. The data are mean ± SEM of three independent experiments. P values < 0.05 were obtained by two-way analysis of variance (ANOVA).
