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AAV2-PlGF1-DE inhibits CNV but AAV2-PlGF1wt does not. CNV volumes were measured by confocal evaluation of Isolectin B4 staining of RPE-choroid flat mounts (4 animals per group). Data are represented as the mean ± SEM. *P = 0.0037 versus AAV2-LacZ; P = 0.0144 versus AAV2-PlGF1wt. Representative pictures of CNV flat mounts. Scale bar: 100 μm.
