Table 2.
Clinical and demographic variables of the population subdivided according to the study
| Total | Mayo | Groningen | Baylor | Lund | CCFP | |
|---|---|---|---|---|---|---|
| No. (row %) | 3622 (100.0) | 1924 (53.1) | 953 (26.3) | 686 (18.9) | 44 (1.2) | 15 (0.4) |
| Age (y) | 54.0 (13.0) | 55.9 (13.4) | 50.6 (12.9) | 53.9 (10.7) | 51.5 (14.1) | 41.3 (16.0) |
| Female sex | 1541 (42.6) | 812 (42.2) | 397 (41.7) | 308 (44.9) | 20 (45.5) | 4 (26.7) |
| Black race | 72 (2.0) | 23 (1.2) | 3 (0.3) | 44 (6.4) | 0 (0.0) | 2 (13.3) |
| Height (cm) | 172.1 (10.4) | 171.5 (10.4) | 173.8 (9.8) | 171.4 (10.9) | 169.8 (9.9) | 175.9 (9.2) |
| Weight (kg) | 83.7 (20.2) | 85.4 (21.8) | 80.6 (15.8) | 84.2 (20.3) | 73.6 (17.1) | 81.5 (17.0) |
| BSA (m2) | 1.96 (0.25) | 1.97 (0.27) | 1.95 (0.21) | 1.96 (0.26) | 1.84 (0.23) | 1.97 (0.20) |
| BMI (kg/m2) | 28.2 (5.9) | 28.9 (6.4) | 26.6 (4.5) | 28.6 (6.0) | 25.4 (4.9) | 26.4 (5.5) |
| Scr (mg/dl) | 1.49 (0.64) | 1.45 (0.60) | 1.56 (0.61) | 1.47 (0.63) | 1.93 (1.63) | 2.07 (1.19) |
| SUN* (mg/dl) | 27.7 (12.8) | 27.7 (12.8) | 33.5 (25.9) | 28.1 (13.9) | 27.9 (21.9) | 36.3 (27.7) |
| GFR (ml/min/1.73 m2) | 55.1 (22.7) | 54.1 (21.6) | 54.6 (20.4) | 59.3 (27.7) | 43.6 (17.1) | 47.0 (28.4) |
| Diabetes | 733 (20.3) | 419 (21.8) | 127 (13.3) | 173 (25.2) | 12 (27.3) | 2 (13.3) |
| Marker | ||||||
| Iohexol | 44 (1.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 44 (100.0) | 0 (0.0) |
| Iothalamate | 3578 (98.9) | 1924 (100.0) | 953 (100.0) | 686 (100.0) | 0 (0.0) | 15 (100.0) |
| Organ | ||||||
| Kidney | 1905 (52.7) | 1027 (53.4) | 869 (91.2) | 0 (0.0) | 0 (0.0) | 9 (60.0) |
| Liver | 1251 (34.6) | 520 (27.0) | 0 (0.0) | 686 (100.0) | 44 (100.0) | 1 (6.7) |
| Lung | 147 (4.1) | 147 (7.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Heart | 110 (3.0) | 33 (1.7) | 74 (7.8) | 0 (0.0) | 0 (0.0) | 3 (20.0) |
| Pancreas | 26 (0.7) | 26 (1.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Multiple organs | 183 (5.1) | 171 (8.9) | 10 (1.0) | 0 (0.0) | 0 (0.0) | 2 (13.3) |
Note: Unless otherwise indicated, values for categorical variables are given as number (column percentage); values for continuous variables, as mean ± standard deviation.
Abbreviation: Mayo; Mayo Clinic, Rochester, Minnesota: Baylor; Baylor University Medical Center, Dallas, Texas, US: Groningen; Groningen Institute for Kidney Diseases, Groningen, Netherlands: Lund; Division of Nephrology, Lund University, Lund, Sweden: CCFP; Cleveland Clinic Foundation Prospective Cohort, Cleveland, Ohio; SUN; serum urea nitrogen; BSA, body surface area; BMI, body mass index; Scr, serum creatinine; GFR, glomerular filtration rate;
SUN reported on 2,858 patients. See Figure S1 for details of patients missing SUN.