Skip to main content
. 2014 Jul 28;9(7):e103253. doi: 10.1371/journal.pone.0103253

Table 2. Determination and interpretation of the MIC values of the antibiotics tested for Escherichia coli (n = 211).

Antibiotic MIC range MIC50 (µg/ml) Interpretation* MIC90 (µg/ml) Interpretation*
Amp/sulb 0.5/0.25–>256/128 16/8 I >256/128 R
Pip/taz ≤0.06/4–>128/4 8/4 S >128/4 R
Cefminox ≤0.06–>128 1 No criteria 128 No criteria
Cefmetazole 0.12–>128 1 S >128 R
Ceftazidime ≤0.03–>64 16 R >64 R
Ceftriaxone ≤0.06–>128 >128 R >128 R
Aztreonam ≤0.06–>128 32 R >128 R
Fosfomycin ≤0.25–>256 0.5 S 4 S
Imipenem ≤0.03–>64 0.12 S 64 R
Meropenem ≤0.06–>128 ≤0.06 S 64 R
Doripenem ≤0.03–>64 ≤0.03 S 64 R
Biapenem ≤0.06–>128 ≤0.06 No criteria 16 No criteria
Amikacin ≤0.06–>128 2 S >128 R
Arbekacin ≤0.06–>128 2 No criteria >128 No criteria
Gentamicin ≤0.06–>128 16 R >128 R
Colistin 0.06–>32 0.25 No criteria 0.5 No criteria

*The interpretation of the MIC50 and MIC90 of all antibiotics tested for all pathogens was performed using the Clinical and Laboratory Standards Institute (CLSI) 2012 guidelines.

Abbreviations: S: susceptible, R: resistant, I: intermediate, amp/sulb: ampicillin/sulbactam, pip/taz: piperacillin/tazobactam, MIC: minimum inhibition concentration.