Figure 6. Concentration/response curves for constructs that resulted in significant amounts of functional AChRs.
Full agonist (ACh) and partial agonists (cytisine, nicotine, and varenicline) were used on (α6β2)2β3 AChRs. Each point is the average response of at least 5 oocytes. Arrows indicate construct 5, that behaves like construct 1, and constructs 6 and 9 that are divergent.