Figure 7. Kinetics of responses to increasing concentrations of ACh by constructs 1 and 5.
A) Concatamer 1 (β3−α6−β2−α6−β2) responds more rapidly with greater currents and more extensive desensitization at higher ACh concentrations. B) Construct 5 (α6211L,α3cyt+β2+β3) response kinetics to ACh are similar, but amplitudes of responses are much larger.