Skip to main content
. Author manuscript; available in PMC: 2014 Jul 28.
Published in final edited form as: J Immunol. 2010 Feb 1;184(5):2677–2685. doi: 10.4049/jimmunol.0903274

Table I.

IC50 at which soluble heparin and LMWH inhibit chemokine binding to immobilized heparin.

KC MIP-2 CXCL8
Heparin 0.142 ± 0.0061 2.8 ± 0.45 2.5 ± 0.45
LMWH 3.83 ± 0.9 59.0 ± 9 31.4 ± 0.3
1

Data represent the concentration (µM) of GAG required to inhibit chemokine (100 nM) binding to heparin immobilized on a sensor surface as determined by SPR. Means ± standard error of the mean are shown for at least 3 independent determinations.