Table 1.
Metabolite | Aging | AD | PD | HD |
---|---|---|---|---|
NAA | ↓ | ↓ | ↓ | |
myo-Inositol | ↑ | ↑ | ↑ | |
Glutamate | ↓ | ↓ | ↑ | ↑ |
Glutamine | ↑ | ↑ | ↑ | |
GABA | ↓ | ↓ | ||
Choline-containing phospholipids | ↑ | ↓ | ↑ | |
Phosphorylethanolamine | ↓ | |||
Taurine | ↓ | ↑ | ||
Lactate | ↑ | ↑ | ↑ |
NAA= N-acetylaspartate; GABA= γ-aminobutyrate; AD= Alzheimer’s disease; PD= Parkinson’s disease; HD= Huntington’s disease.
Direction of the arrow indicates either increase ( ↑) or decrease ( ↓) of metabolite concentration.