Table 8.
Genotype distribution and allele frequency in IBS-D subgroup and the control group.
| IBS-D (n=46) n (%) | Control group (n=115) n (%) | Statistics | |
|---|---|---|---|
| GNβ3 genotype | |||
| CC | 36 (78.3) | 92 (80.0) | |
| CT | 8 (17.4) | 21 (18.3) | |
| TT | 2 (4.3) | 2 (1.7) | P=0.687* |
| GNβ3 allele | |||
| C | 80 (87.0) | 205 (89.1) | χ2=0.305, P=0.581 |
| T | 12 (13.0) | 25 (10.9) | |
| COMT genotype | |||
| G/G | 39 (84.8) | 101 (87.8) | |
| G/A | 1 (2.2) | 13 (11.3) | |
| A/A | 6 (13.0) | 1 (0.9) | P=0.001* |
| COMT allele | |||
| G | 79 (85.9) | 215 (95.3) | χ2=4.79, P=0.0290.052 |
| A | 13 (14.1) | 15 (6.5) | |
*
Using Fisher’s exact test.