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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Trends Neurosci. 2014 Jun 5;37(7):399–407. doi: 10.1016/j.tins.2014.05.003

Figure 1.

Figure 1

Positive (right) and negative (left) regulators of activity-dependent changes in dendritic morphology. Neuron images are 5 DIV cultured rat cortical neurons transfected with a GFP-expressing plasmid and treated with nifedipine (left), untreated (center), or treated with potassium chloride (right) (for further details, see [14]). While the net effect of increased activity is increased complexity (right), a number of molecules that either enhance or inhibit the dendritic arbor are upregulated and contribute to the net change.