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Nanoparticle Characterization
| Control NP | Method A | Method B | |
|---|---|---|---|
| Hydrodynamic diameter (nm) (mean ± SD), n = 3 | 299.6 ± 0.9 | 311.0 ± 9.2 | 325.8 ± 6.7 |
| Polydispersity index | 0.13 | 0.14 | 0.15 |
| Zeta potential (mV) (mean ± SD), n = 3 | −8.5 ± 0.3 | −9.9 ± 0.5 | −9.6 ± 0.4 |
| Carboplatin loading (μg/mg NP) | – | 1.3 | 3.4 |
| Encapsulation efficiency (%) | – | 1.5 | 3.9 |
