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. 2014 Apr 30;15(4):928–938. doi: 10.1208/s12249-014-0124-9

Table III.

Vaginal Histopathology in Progesterone-Conditioned CD-1 Mice

Histopathology Parameter Vehicle N-9 BZK TA 1/ SR-2P TA 2 TA 3
Epithelial Thinning 0 1.2 a 2.2 a 0.8 1.6 1
Erosion 0 0.6 2.6 0 0.8 0
Exudate 0.4 0.2 1.6 0 0.8 1.2
Hemorrhage 0 0 0 0.6 0 0.4
Leukocyte Infiltration 0 0.8 2.2 1.8 3 3
Keratinization 0 0.2 0.2 0 0 0
Mucification 3.4 0.8 0.8 2.6 2 1.6

aMinimal changes ≥0.5 are highlighted in italics and major changes ≥2 are highlighted with underline