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The deposition of collagen in the atrial interstitium in Masson-stained sections of the control, diabetic and diabetic rats treated with fasudil (DM+fas). Heart tissues from the diabetic group show focal regions of fibrosis (blue) in the interstitium (P<0.01 vs. the control and DM+fas groups). Magnification, ×400. The number of rats in each group was six.
