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. 2014 Jul 14;8(3):836–840. doi: 10.3892/etm.2014.1843

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Copyright © 2014, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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The mRNA expression levels of (A) type I and (B) type III procollagen in untreated diabetic, control and DM+fas rats was evaluated by quantitative polymerase chain reaction. The intensities of type I and III procollagen were standardized to that of GAPDH. The number of rats in each group was six. The mRNA expression levels of type I and III procollagen were significantly increased in diabetic rats and decreased in DM+fas rats. ^*P<0.01 vs. control rats,^**P<0.01 vs. diabetic rats. DM+fas, diabetic treated with fasudil.